Sermorelin 5mg

Sermorelin 5mg is a synthetic 29-amino acid peptide representing the biologically active N-terminal fragment of endogenous Growth Hormone-Releasing Hormone (GHRH), available at ≥98% purity from The Peptide Store. Engineered as a precision-grade lyophilized research compound, this formulation is designed exclusively for advanced laboratory investigation of pituitary somatotroph regulation and somatotropic axis dynamics. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

Sermorelin 5mg is one of the most widely studied GHRH-derived peptides in contemporary endocrinology and neuroendocrine research. As a truncated analog comprising the first 29 amino acids of the naturally occurring 44-residue GHRH molecule, Sermorelin retains the full receptor-binding capacity required to activate pituitary GHRH receptors. Researchers investigating hypothalamic-pituitary axis signaling, somatotroph cell biology, and growth hormone secretion dynamics consistently rely on this compound as a gold-standard research tool. The Peptide Store offers this compound in a rigorously quality-controlled, lyophilized format, ensuring molecular integrity from order fulfillment through laboratory application.

Peptide Structure & Amino Acid Sequence

Sermorelin is structurally defined as GHRH(1–29)-NH₂, encompassing the first 29 amino acids of human growth hormone-releasing hormone with a C-terminal amide group. This specific truncation preserves the complete pharmacophoric region responsible for GHRH receptor (GHRHR) recognition and activation. The linear sequence is: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂. The molecular formula is C₁₄₉H₂₄₆N₄₄O₄₂S, with a molecular weight of approximately 3,357.96 Da. The CAS registry number for Sermorelin is 86168-78-7.

Chemical & Physical Characteristics

Sermorelin presents as a white to off-white lyophilized powder under standard laboratory conditions. Key physicochemical properties include:

• Molecular Formula: C₁₄₉H₂₄₆N₄₄O₄₂S
• Molecular Weight: ~3,357.96 Da
• CAS Number: 86168-78-7
• Form: Lyophilized powder
• Solubility: Soluble in aqueous buffers at appropriate pH for research purposes
• Storage Temperature: −20°C (long-term); 2–8°C (short-term)
• Appearance: White to off-white powder

Purity & Analytical Verification (HPLC & MS)

Every batch of Sermorelin 5mg supplied by The Peptide Store is independently verified to achieve ≥98% purity by reverse-phase High-Performance Liquid Chromatography (RP-HPLC). Mass spectrometry (MS) analysis is additionally employed to confirm molecular identity, sequence integrity, and the absence of truncated or modified byproducts. These dual-verification protocols ensure that researchers receive a compound of consistent, publication-grade quality suitable for reproducible experimental outcomes.

Quality Control & Lyophilization Integrity

The lyophilization process employed for Sermorelin 5mg is conducted under controlled conditions to eliminate residual moisture while preserving the three-dimensional structural conformation of the peptide. Lyophilization minimizes oxidative degradation, prevents aggregation, and extends shelf stability significantly compared to solution-phase formulations. Each vial undergoes integrity testing prior to dispatch, confirming that the lyophilized cake remains intact, visually uniform, and free from particulate contamination.

Safety, Handling & Laboratory Precautions

Sermorelin 5mg is a research-grade compound intended solely for qualified laboratory professionals operating within appropriately equipped research facilities. Standard laboratory safety protocols should be observed at all times, including the use of personal protective equipment (PPE) such as gloves, eye protection, and lab coats. Researchers should consult applicable institutional biosafety guidelines and relevant Safety Data Sheets (SDS) prior to handling. This compound is not approved for any human or animal administration under any circumstances.

Reconstitution, Packaging & Storage

Sermorelin 5mg is supplied as a lyophilized powder in a sealed, sterile vial suitable for research laboratory use. Reconstitution should be performed using appropriate aqueous solvents as determined by the specific research protocol in use. Upon reconstitution, the resulting solution should be handled, aliquoted, and stored in accordance with validated laboratory procedures. Long-term storage of the lyophilized form is recommended at −20°C, away from light and moisture. Short-term storage at 2–8°C is acceptable for active research periods. Repeated freeze-thaw cycles should be avoided to preserve peptide integrity.

Intended Research Use & Market Positioning

Sermorelin 5mg is positioned as a premier research tool for in vitro and in vivo laboratory studies focused on hypothalamic-pituitary signaling, somatotroph biology, neuroendocrine axis modeling, and growth hormone secretagogue pharmacology. It is widely referenced in peer-reviewed literature and represents an essential compound for endocrinology research programs. The Peptide Store offers Sermorelin 5mg for sale at a competitive best price, making it accessible to academic institutions, contract research organizations, and independent research laboratories seeking reliable, high-purity peptides.

Ordering, Availability & Fulfillment

Researchers can buy Sermorelin 5mg online directly through The Peptide Store with confidence. Orders are processed promptly and fulfilled with careful attention to cold-chain packaging integrity during transit. The Peptide Store maintains consistent inventory availability and offers a streamlined ordering experience for research institutions and qualified buyers. Order now to secure your supply of this high-demand research peptide at the best price available.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Sermorelin 5mg is sold exclusively as a laboratory research reagent. It has not been evaluated or approved by any regulatory authority for therapeutic, prophylactic, or diagnostic use in humans or animals. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international laws and regulations governing the acquisition, possession, and use of research peptides. The Peptide Store assumes no liability for misuse, improper handling, or any application of this compound outside the scope of legitimate scientific research.